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azoturia or tying up
"Tying-Up", "Setfast", "Monday Morning Disease", "Azoturia" or
Equine Rhabdomyelosis... are all names for a painful condition that affects the muscles of horses ; ranging from mild stiffness and cramps to being unable to move or even stand up.
The basic disease is not very well understood and it is probable that "triggering" factors are different for different horses with different work regimes.
There are a number of anecdotal theories about the best way to prevent the problem occurring – but not much clinical proof, as episodes vary so much.
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